The tenth week of the 2020 college football season is the first week in which all conferences will take part, as the Pac-12 opens their slate on November 7. Did you have Michigan State beating Michigan? We had the cover….but not the straight up win. Did you have Penn State opening at 0-2, We had them at 1-1. What happened to Navy’s ironclad defense? They got torched for 51 points in the first three quarters by SMU. Oh, and did you have Oklahoma State losing to Texas? We did not…and also didn’t have the Cowboys turning the ball over four times.
What will unfold in Week 10? We have your college football betting picks against the spread.
NCAA News: Week 10 ATS Picks
Clemson (-6.5) at Notre Dame
This line seems more than a little off-kilter. Clemson won’t have Trevor Lawrence, as the cardiac testing protocols required by the ACC for players who have tested positive for COVID-19 won’t be done in time. That means that the Tigers are heading to South Bend with their backup quarterback — and are still favored by almost a touchdown. Remember that Clemson fell behind BC, 28-10, at home on Saturday and needed the largest comeback in school history to eke out a 34-28 win. Notre Dame comes in ranked fourth in the nation and is unbeaten. The Tigers’ backup quarterback, D.J. Uiagalelei, is a true freshman. He showed plenty of poise in the comeback, but the Fighting Irish won’t allow the Tigers to dig out of a hole that size. Noter Dame to cover. | Bet on the Game Now!
Florida (+4.5) at Georgia
This is basically the play-in for the SEC East entrant in the SEC Championship. Florida had a huge brawl on Saturday in their game against Missouri, and the conference has yet to announce suspensions…which would affect the line. Those movements would only make this point spread bigger, so if you think Georgia will win, then you should lock that wager in now. Remember that Georgia went to Kentucky and only mustered 14 points. They only gave up three, but the problems of the Bulldog offense remain a major question for this program. Georgia to win and cover. | Bet on the Game Now!
Stanford (+11.5) at Oregon
The Pac-12 will play just a seven-game regular season, which means that if the champion is going to make the College Football Playoff, it will likely need seven convincing wins, plus another convincing win in the Pac-12 title game. Oregon will need to take the game to Stanford and deliver in a big win — but given how poorly defenses have played in their opening weeks, will the Ducks be able to pull away by two touchdowns? Stanford to cover. | Bet on the Game Now!
BYU (-2.5) at Boise State
BYU has been a single-digit favorite twice this season, against Navy and Houston. They beat Navy by 52 points and beat Houston by 17. BYU is currently ranked ninth, but playing as an independent has meant that their strength of schedule has suffered immensely, as the Power 5 conferences all opted to play conference-only schedules this year. The Cougars need this win in order to sniff a shot at a Group of Five bowl bid. BYU to win and cover. | Bet on the Game Now!
Michigan (-3.5) at Indiana
Michigan has a 24-game winning streak going against the Hoosiers, and they’re likely to have some frustration to work out after losing at home to Michigan State this past weekend. However, Indiana comes in unbeaten and, with a win, would make a statement that they are the best Big Ten team other than Ohio State, due to the growing spread of COVID-19 in the Wisconsin program. Hoosiers to cover. | Bet on the Game Now!
Houston (+10.5) at Cincinnati
The Bearcats have dealt with the two top teams in the AAC West the last two weeks (SMU and Memphis) and won those two games by a combined 65 points. Houston comes in with a fun offense, but their problems on defense should lead to another huge point total — and to another big Cincinnati win. Cincinnati to win and cover. | Bet on the Game Now!
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