2019 NFL Week 6 Odds, Overview & Picks for Every Game

The demolition of the Cleveland Browns by the San Francisco 49ers — complete with Joey Bosa’s mock flag plant, getting some rhetorical revenge against Baker Mayfield for his gesture when Mayfield played for Oklahoma and led his team to an upset of Bosa’s Ohio State Buckeyes and planted the Sooner flag at midfield — was not something that many expected. Carolina backup quarterback Kyle Allen is now 4-0 as a starter — at what point will the Panthers have a quarterback controversy?  Teddy Bridgewater, who is starting for Drew Brees until Brees’ thumb is ready, threw for 314 yards and four touchdowns, the most yards he has amassed in a game since 2015. Those were just some of the big storylines in Week 5 of the 2019 NFL campaign. Want some sports betting insights for NFL Week 6? Check out our NFL betting picks for the week ahead.

2019 NFL Week 6 Odds, Overview & Picks for Every Game

Week 6 Power Rankings: 1. @Patriots 2. @Saints 3. @Chiefs 4-32: https://t.co/4f3r2W6yMm (via @DanHanzus) pic.twitter.com/hBZdUGdkgE

— NFL (@NFL) October 8, 2019

• Bye: Buffalo, Chicago, Indianapolis, Oakland

Thursday, October 10 (8:20pm ET, FOX/NFL Network)

N.Y. Giants (+16.5) at New England (O/U 43)

The Giants just lost by 18 to the Vikings at home. New England just beat Washington by 26 on the road. People are figuring the Giants’ Daniel Jones, which does not bode well against one of the NFL’s top defenses. Patriots to win and cover.

Sunday, October 13 (9:30am ET)

Carolina (-2) vs Tampa Bay (48.5) (in London)

The Buccaneers followed up their big win over the Rams with a loss to the Saints in Tampa Bay — but only by seven points. Carolina got 176 yards from Christian McCaffrey in their win over Jacksonville, as Kyle Allen continues to excel at managing games. Panthers to win and cover.

Sunday, October 13 (1:00pm ET)

Cincinnati (+11.5) at Baltimore (48.5)

Baltimore has been routed by Cleveland at home and barely escaped Pittsburgh with an overtime win — even though the Steelers were down to their third-string quarterback by the end. They should roll Cincinnati, though, after the Bengals lost at home to Arizona. Ravens to win and cover.

Seattle (PK) at Cleveland (47)

Which Browns will show up? The ones that routed the Ravens or the ones who got destroyed by San Francisco? As long as this remains a pick’em, I’m going with the Seahawks, who just edged the Rams last Thursday. Seahawks to win and cover.

New Orleans (+1) at Jacksonville (45)

Despite Minshew Magic, Jacksonville lost at home to Kyle Allen’s Panthers by seven last week. I think Teddy Bridgewater’s Saints can do just as well, if not better. Saints to win and cover.

Houston (+5.5) at Kansas City (55.5)

Deshaun Watson torched the Atlanta Falcons for 426 yards in a 53-32 win. Kansas City’s defense has been getting gashed by the run, so Carlos Hyde should get more than 60 yards this week. But can the Texans provide the sort of pass rush that the Colts used to beat Kansas City this past week? Chiefs to win and cover.

Washington (-3.5) at Miami (41)

Washington heads to Miami with an interim coach and major question marks at quarterback. Miami comes out of the bye, but are they ready for anyone yet? If Miami is going to win a home game, it should be against a Redskins team that is in disarray. Dolphins to cover.

Philadelphia (+3) at Minnesota (44)

The Eagles’ offense figured out how to work through that Green Bay defense and put together a terrific win two weeks ago, and then they routed the Jets at home this past weekend. Yes, the Vikings beat the Giants easily this week, but I’m not sure they can stop the Eagles. Eagles to cover.

Sunday, October 13 (4:05pm ET)

Atlanta (-1.5) at Arizona (52)

Can Kyler Murray deliver a cover against a struggling Falcons team at home? Yes he can. Cardinals to cover.

San Francisco (+4) at L.A. Rams (49)

That Ram defense gave up 30 points in Seattle. Jimmy Garoppolo brings the 49ers down with a full head of steam after embarrassing Cleveland on Monday Night Football. The Rams could win late, but I will take San Francisco to cover.

Sunday, October 13 (4:25pm ET)

Tennessee (+2.5) at Denver (38.5)

Tennessee could only muster seven points at home against the Bills (who do have an elite defense). Denver went to L.A. and delivered an impressive win over the Chargers. I see the Broncos delivering again at home. Broncos to win and cover.

Dallas (-9) at N.Y. Jets (43.5)

Dallas has shown that it can beat the lower teams in the league easily — but then struggles to move the ball when challenges come. The Jets are one of the lower teams, to be sure. Cowboys to win and cover.

Sunday, October 13 (8:20pm ET, NBC)

Pittsburgh (+6.5) at L.A. Chargers (41)

Mason Rudolph is back at work, but he’s still in the concussion protocol. So the Steelers, at least for now, head west with a third-string quarterback on the job. The Chargers should be able to handle that. Chargers to win and cover.

Monday, October 14 (8:15pm ET, ESPN)

Detroit (+4.5) at Green Bay (47)

Detroit almost beat Kansas City with a solid running attack and a huge night from Matthew Stafford. The Packers’ defense showed some holes late against Philadelphia and then against Dallas. However, playing at Lambeau should give the Packers the momentum they need to win here. Packers to win and cover.