NFL Preseason Odds: The last week of the NFL preseason generally focuses on weeding out the bottom of the depth chart and keeping starters healthy. The danger is real when it comes to season-ending injuries; the Week 2 preseason game between New England and Green Bay was suspended early in the fourth quarter after Patriots cornerback Isaiah Bolden suffered from an apparent head injury and was strapped to a backboard before being carted off the field. This makes sports betting even riskier than usual as players who will not play any meaningful downs in the regular season will likely determine game outcomes this weekend. We have NFL picks for each matchup, but we don’t recommend putting down a lot of money on the NFL this weekend.
NFL Preseason Odds and Lines: Week 3 Odds Picks | Bet American Football Betting Lines
Pittsburgh Steelers vs Atlanta Falcons
NFL Preseason Odds: Pittsburgh Steelers (-4.5) at Atlanta Falcons
When: Thursday, August 24 at 7:30 pm ET
Where: Mercedes-Benz Stadium, Atlanta, GA
TV / Streaming: NFL Network
The Steelers are likely to let Kenny Pickett lead a couple of series on offense before going to the backups, but the first backup is Mitch Trubisky, who has NFL starting experience. The Steelers’ defense should be able to line up and stop the run-first Falcon offense for enough of the game to get the win. Steelers to win and cover.
Bet on the Pittsburgh Steelers vs Atlanta Falcons
NFL Preseason Odds | Indianapolis Colts vs Philadelphia Eagles
NFL Preseason Bets: Indianapolis Colts (-5) at Philadelphia Eagles
When: Thursday, August 24 at 8:00 pm ET
Where: Lincoln Financial Field, Philadelphia, PA
TV / Streaming: Prime Video
The Colts need to let Anthony Richardson get more time at quarterback as the rookie starter is getting his NFL legs under him. The Eagles can rest and start their NFC East title defense in Week 1. Colts to win and cover.
Bet on the Indianapolis Colts vs Philadelphia Eagles
Detroit Lions vs Carolina Panthers
NFL Preseason Odds: Detroit Lions (+4.5) at Carolina Panthers
When: Friday, August 25 at 8:00 pm ET
Where: Bank of America Stadium, Charlotte, NC
TV / Streaming: CBS
The Panthers also have a rookie starting quarterback in Bryce Young, so expect him to get some time to pick apart the backups on the Detroit defense. Panthers to win and cover.
Bet on the Detroit Lions vs Carolina Panthers
NFL Preseason Odds | New England Patriots vs Tennessee Titans
NFL Preseason Bets: New England Patriots (-2) at Tennessee Titans
When: Friday, August 25 at 8:15 pm ET
Where: Nissan Stadium, Nashville, TN
TV / Streaming: NFL Network
I don’t expect to see Ryan Tannehill or Derrick Henry out there for the Titans. Will Bill Belichick make new tailback Ezekiel Elliott take the field? Patriots to win and cover.
Bet on the New England Patriots vs Tennessee Titans
NFL Preseason Odds | L.A. Chargers vs San Francisco 49ers
NFL Preseason Bets: L.A. Chargers (+7.5) at San Francisco 49ers
When: Friday, August 25 at 10:00 pm ET
Where: Levi’s Stadium, Santa Clara, CA
TV / Streaming: NFL Network
I like Trey Lance to do more with the 49ers’ offense than I think Easton Stick will do with the Chargers’ attack. But is a line of more than a touchdown reasonable, given the morass of backups who will play in the second half? Chargers to cover.
Bet on the L.A. Chargers vs San Francisco 49ers
Buffalo Bills vs Chicago Bears
NFL Preseason Odds: Buffalo Bills (+1.5) at Chicago Bears
When: Saturday, August 26 at 1:00 pm ET
Where: Soldier Field, Chicago, IL
TV / Streaming: –
The Bills shouldn’t risk Josh Allen or any other offensive skill players in their visit to Soldier Field. The Bears should protect Justin Fields as well, but the Bears’ roster has more questions to answer, so I expect their effort to be higher. Bears to win and cover.
Bet on the Buffalo Bills vs Chicago Bears
NFL Preseason Odds | Seattle Seahawks vs Green Bay Packers
NFL Preseason Bets: Seattle Seahawks (+3) at Green Bay Packers
When: Saturday, August 26 at 1:00 pm ET
Where: Lambeau Field, Green Bay, WI
TV / Streaming: –
The Packers are basically getting the three points that home teams usually receive as part of setting the point spread. Pete Carroll has long been more competitive in preseason games than many of his coaching peers. Seahawks to cover.
Bet on the Seattle Seahawks vs Green Bay Packers
NFL Preseason Odds | Cleveland Browns vs Kansas City Chiefs
NFL Preseason Bets: Cleveland Browns (-2) at Kansas City Chiefs
When: Saturday, August 26 at 1:00 pm ET
Where: GEHA Field at Arrowhead Stadium, Kansas City, MO
TV / Streaming: NFL Network
I like the Browns’ action at backup quarterback more than I like Chad Henne to put up big numbers for the Chiefs. Browns to win and cover.
Bet on the Cleveland Browns vs Kansas City Chiefs
Arizona Cardinals vs Minnesota Vikings
NFL Preseason Odds: Arizona Cardinals (+1.5) at Minnesota Vikings
When: Saturday, August 26 at 1:00 pm ET
Where: U.S. Bank Stadium, Minneapolis, MN
TV / Streaming: –
Given the lack of NFL-level talent on the Cardinals roster at this point, I’m not betting on them for the foreseeable future. Vikings to win and cover.
Bet on the Arizona Cardinals vs Minnesota Vikings
NFL Preseason Odds | N.Y. Jets vs N.Y. Giants
NFL Preseason Bets: N.Y. Jets (-4.5) at N.Y. Giants
When: Saturday, August 26 at 6:00 pm ET
Where: U.S. Bank Stadium, Minneapolis, MN
TV / Streaming: NFL Network
Zach Wilson is a much better quarterback option for the Jets than the Giants’ backup will be. However, both teams have positive momentum going into 2023, and both will leave their top skill players on the sidelines. Giants to cover.
Bet on the N.Y. Jets vs N.Y. Giants
Cincinnati Bengals vs Washington Commanders
NFL Preseason Odds: Cincinnati Bengals (+4.5) at Washington Commanders
When: Saturday, August 26 at 6:05 pm ET
Where: FedExField, Landover, MD
TV / Streaming: –
The Bengals are resting Joe Burrow and Ja’Marr Chase and primarily avoiding key injuries, so they shouldn’t be that interested in hanging with Washington. Commanders to win and cover.
Bet on the Cincinnati Bengals vs Washington Commanders
Baltimore Ravens vs Tampa Bay Buccaneers
NFL Preseason Odds: Baltimore Ravens (+1.5) at Tampa Bay Buccaneers
When: Saturday, August 26 at 7:00 pm ET
Where: Raymond James Stadium, Tampa, FL
TV / Streaming: –
We have two teams with veteran quarterbacks, but the Ravens have that long preseason winning streak to maintain. Ravens to cover.
Bet on the Baltimore Ravens vs Tampa Bay Buccaneers
Miami Dolphins vs Jacksonville Jaguars
NFL Preseason Odds: Miami Dolphins (+6) at Jacksonville Jaguars
When: Saturday, August 26 at 7:00 pm ET
Where: TIAA Bank Field, Jacksonville, FL
TV / Streaming: –
This is a pretty big spread given that both teams will likely be resting their top offensive skill players. Dolphins to cover.
Bet on the Miami Dolphins vs Jacksonville Jaguars
Las Vegas Raiders vs Dallas Cowboys
NFL Preseason Odds: Las Vegas Raiders (-5) at Dallas Cowboys
When: Saturday, August 26 at 8:00 pm ET
Where: TIAA Bank Field, Jacksonville, FL
TV / Streaming: –
Dallas rarely shows interest in winning preseason games, so I expect the Cowboys to play a lot of the bottom of the depth chart tonight. Raiders to win and cover.
Bet on the Las Vegas Raiders vs Dallas Cowboys
L.A. Rams vs Denver Broncos
NFL Preseason Odds: L.A. Rams (+6) at Denver Broncos
When: Saturday, August 26 at 9:00 pm ET
Where: TIAA Bank Field, Jacksonville, FL
TV / Streaming: NFL Network
John Wolford is injured for the Rams, so it will be their practice squad quarterbacks running things. Broncos to win and cover.
Bet on the L.A. Rams vs Denver Broncos
Houston Texans vs New Orleans Saints
NFL Preseason Odds: Houston Texans (+3.5) at New Orleans Saints
When: Sunday, August 27 at 8:00 pm ET
Where: Caesars Superdome, New Orleans, LA
TV / Streaming: NFL Network
Houston might have the better coaching staff in this game, so I am going to take the very rare step of picking the Texans. Texans to cover.
Bet on the Houston Texans vs New Orleans Saints
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