The Dallas Cowboys headed to San Francisco for a prime-time showdown with the 49ers on Sunday night, and the 42-10 whipping that the 49ers delivered showed a clear gap between the two teams. Team owner Jerry Jones noted, “We ran into an outstanding team, and we didn’t play well…We have players on field and on the roster that can get it done.” Meanwhile, San Francisco wide receiver Deebo Samuel warned the media that a rematch between the two teams might turn out even worse for the Cowboys. Moving into Week 6, don’t miss our NFL Parlay Picks.
2023 NFL Parlay Picks for Week 6. The 32-point beating was the second-worst loss of Dallas coach Mike McCarthy’s career and the largest that Dak Prescott has endured as the Cowboys’ starting quarterback.
| Week 6 NFL Odds and Parlay Pick | |
|---|---|
| Broncos (+10.5) vs Chiefs (O/U 50.5) | |
| Colts (+4.5) vs Jaguars (O/U 45.5) | |
| 49ers (-4.5) vs Browns (O/U 40) | |
| Saints (-2.5) vs Texans (O/U 40) | |
| Eagles (-6.5) vs Jets (O/U 42.5) | |
NFL Parlay Pick Denver Broncos at Kansas City Chiefs TNF
When: Thursday Night Football, October 12 at 8:15 pm ET
Where: GEHA Field at Arrowhead Stadium, Kansas City, MO
TV / Streaming: Prime Video
Patrick Mahomes is a perfect 11-for-11 in wins over the Denver Broncos as the Chiefs’ starting quarterback, by far his best slate against any league opponent. The Broncos have an awful defense right now, as they gave up an historic 70 points to the Miami Dolphins and even saw the Jets score 31 last week. Denver has just one win this season, a comeback barnburner in Chicago. Travis Kelce had a low ankle sprain on Sunday, and he practiced on Tuesday but remains questionable for Thursday. Even with Kelce limited, the Chiefs have a dynamic offense and a pass rush that can harass Russell Wilson into yet another poor performance.
Parlay Pick: Chiefs to win and cover / Take the over.
NFL Parlay Picks Indianapolis Colts at Jacksonville Jaguars
When: Sunday, October 15 at 1:00 pm ET
Where: EverBank Stadium, Jacksonville, FL
TV / Streaming: CBS
The Jaguars return from a two-week stint in London without the benefit of a bye week, and their first task is a rematch of their earlier win over the Colts. Anthony Richardson (right shoulder) is out, meaning that Gardner Minshew gets to take on his former team. The problem for the Colts is that their secondary will struggle against Trevor Lawrence and Calvin Ridley. The Colts did get back Jonathan Taylor at tailback (fresh with a contract extension), but will he be able to do damage against a tough Jacksonville run defense?
Parlay Pick: Jaguars to win and cover.
NFL Parlay Pick San Francisco 49ers at Cleveland Browns
When: Sunday, October 15 at 1:00 pm ET
Where: Cleveland Browns Stadium, Cleveland, OH
TV / Streaming: FOX
The San Francisco offense already demolished one of the NFL’s top defenses when they dismantled Dallas last week. Brock Purdy has a number of healthy offensive weapons around him, so even though they have a tough Browns defense ahead of them, they have a rhythm in the running and passing game that keeps opposing units guessing. Also, the Browns have two important players – Myles Garrett and Deshaun Watson – dealing with injuries.
Parlay Pick: 49ers to win and cover.
NFL Parlay Picks New Orleans Saints at Houston Texans
When: Sunday, October 15 at 1:00 pm ET
Where: NRG Stadium, Houston, TX
TV / Streaming: FOX
New Orleans demolished New England last week, 34-0. Alvin Kamara is back to key the running game, and the Saints’ defense gets tougher and more disciplined each week. A problem, though, is that the Saints are having to work around Derek Carr instead of leveraging him for big plays. The blocking is a bit questionable in New Orleans, and the Texans can load up against the run. Also, C.J. Stroud has shown strong ball security instincts so far while running the Houston offense. However, the Saints’ defense will bring him challenges.
Parlay Pick: Saints to win and cover.
NFL Parlay Pick Philadelphia Eagles at N.Y. Jets
When: Sunday, October 15 at 4:25 pm ET
Where: MetLife Stadium, East Rutherford, NJ
TV / Streaming: FOX
The Jets picked up a huge win in Denver, and the Eagles have to travel on a short week. However, the Eagles showed how their front seven could rattle Matthew Stafford last week against the Rams, and they should be able to do the same to Zach Wilson. Breece Hall ran wild for the Jets last week, but the Eagles should be able to bottle him up. The Jets also have a stout defense, but the Eagles have the line to spring D’Andre Swift and give Jalen Hurts time in the pocket.
Parlay Pick: Eagles to win and cover.
Odds to Win Conference Championship
AFC Championship
| AFC Team | Odds |
|---|---|
| Kansas City Chiefs | +285 |
| Buffalo Bills | +370 |
| Miami Dolphins | +530 |
| Baltimore Ravens | +650 |
| Los Angeles Chargers | +1325 |
| Cleveland Browns | +1450 |
| Cincinnati Bengals | +1475 |
| Jacksonville Jaguars | +1475 |
| Tennessee Titans | +3100 |
| Pittsburgh Steelers | +3400 |
| New England Patriots | +5000 |
| Denver Broncos | +6000 |
| New York Jets | +6200 |
| Houston Texans | +6200 |
| Indianapolis Colts | +6600 |
| Las Vegas Raiders | +8500 |
| AFC Lines to Win | |
NFC Championship
| NFC Team | Odds |
|---|---|
| San Francisco 49ers | +222 |
| Philadelphia Eagles | +285 |
| Dallas Cowboys | +430 |
| Detroit Lions | +780 |
| Seattle Seahawks | +1625 |
| New Orleans Saints | +1925 |
| Green Bay Packers | +2600 |
| Atlanta Falcons | +2800 |
| Tampa Bay Buccaneers | +2900 |
| Minnesota Vikings | +2900 |
| Los Angeles Rams | +4000 |
| Washington Commanders | +7000 |
| New York Giants | +7500 |
| Chicago Bears | +11000 |
| Carolina Panthers | +15000 |
| Arizona Cardinals | +17000 |
| NFC Lines to Win | |
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